Vaginal drugs on the agenda
One of the topics that have been extensively researched recently is vaginal drug applications. For many years, the vaginal environment was thought to be a completely isolated and impermeable structure.
From here, the idea that drug applications were useless became widespread. Subsequent data showed that the vaginal drugs were absorbed in the same way as in the stomach. Especially after the menopause drugs / hormones used in the blood passes through the vagina easily.
What are the advantages of vaginal drugs?
The absorption of drugs from the patches applied to the skin is affected by the patient's weight. So the absorption of overweight patients is reduced. However, the weight of the patient is not effective in the drugs applied to the vagina. vaginal absorption does not change. At the same time, vaginal drug delivery times are long and more stable without the level of changes they provide in the blood. The doses used are also lower. Considering all this, vaginal drug applications have become more popular.
l Will vaginal drugs damage the vagina? Which medications are administered through the vagina?
Previously, only postmenopausal hormone drugs were intended for vaginal administration, but later they were used as prolactin-lowering drugs (dopamine) and Viagra was used vaginally to thicken the uterine layer. Also called indomethacin and used as a pain medication to prevent premature birth is given vaginally. Drugs have a very low risk of disrupting the acidic structure of the vagina and causing discharge.
l Can solutions be used?
Since the solutions used for vaginal cleaning are acidic, they can be applied for a period of time. However, they need not be used for a long time.
l Is the structure of the vagina suitable for drug intake?
It was found that the vagina showed a structure parallel to the floor when the woman was standing, not perpendicular to the floor. Therefore, the possibility of a drug administered deep into the vagina is very weak. Technically, however, it is natural for some women to have difficulty applying it. But the application technique can be taught.
l Can you give us information about vaginal rings?
It was seen that low dose hormones used as birth control method could be loaded into a ring-shaped plastic tube and applied to the vagina in this way. Silicone rings are placed in the back of the vagina and remain there for 28 days. Then a week's break is taken and replaced with a new one. Men don't feel it during the relationship. Thus, women get rid of the obligation to take medication every day. This method, which has a low incidence of side effects, will become widespread in our country in the near future.
What are the expected improvements in vaginal medications in the future?
In the future, vaginal applications (in monthly capsules) of the depot form of medications that need to be continuously administered (eg cardiac medicines, sugar-lowering medications, etc.) will also be on the agenda. In addition, the prevention of urinary incontinence drugs, AIDS-causing viruses or drugs that prevent the transmission of Herpes virus is also being studied for vaginal use.
l How should vaginal cleaning be provided?
Millions of bacteria live together in the vagina. The acid of the medium prevents one of them from overgrowing. In addition, the defense system in the vagina is very advanced. This also reduces the risk of germs contamination during sexual intercourse. But it does not reduce to zero. It is not suitable to apply soap to the inner parts for vaginal cleaning as this will damage the environment. The most convenient application to be wiped only with warm water.
9AXX
Always Ultra Thin, Size 1, Regular Pads, Unscented 44 Count, Pack of 3
