Horrible Methods Used by Physicians Before Inventing Modern Pregnancy Tests!
Let's say you think you might be pregnant. Naturally you go to the pharmacy, you get a urine test; and the result: You can immediately find out if there is a growing person in you.
However, pregnancy tests that you have in mind right now are relatively new discoveries. But how did women learn that they were expecting a baby before? It seems that the old “pregnancy tests çok were far more strange and unreal than you might have imagined. If you're eating right now, you might want to take a break, and things will get a little weird.
Al News From “Small”
Let's first look at some basic information. When a woman becomes pregnant, her hormone levels change. At the beginning of pregnancy, human chorionic gonadotropin hormone (hCG) is secreted by a portion of the placenta. This hormone works together with other parts of the body to maintain the presence of the corpus luteum at the beginning of each menstrual cycle. It also triggers the production of progesterone, a multipurpose hormone that contributes to the maintenance of pregnancy, especially in the early stages.
A contemporary pregnancy test may detect signs of elevated hCG levels in the urine of the woman from six days after fertilization. These tests produce very little pozitif false positive ”results and are incredibly accurate (99%). Some types control more than one hormone produced during pregnancy rather than pure hCG.
Urine Pre-Cogs
At one time, the urine of women thought to be pregnant was examined by ”seers yerine instead of physicians or advanced technology pregnancy tests. European women in the 16th century; they were tricked by the “experts eden who looked carefully at the disgusting yellow currents and evaluated the color, tone and smell of the urine to determine whether they were expecting a baby.
As part of this practical method, the more advanced seers used to mix urine with wine. Although they probably didn't know how, there was a scientific fact behind this: that alcohol reacted with some special proteins produced during pregnancy, and the urine consistency changed.
This urine examination technique, also called “uroscopy ır, dates back to ancient Babylon and was transferred to Byzantine medicine thanks to the progress of the Eastern Roman Empire from the 5th to the mid-15th century.
Egyptian Recruitment
In fact, urine tests appeared much earlier than the Protestant Reformation and Copernicus. The ancient Egyptians, who lived in the 14th century BC, that is approximately 3,350 years ago, also had their own methods.
During the reign of Pharaoh Akhenaten, the husband of the notorious Queen Nefertiti, the Egyptians sprinkled her urine on wheat and barley seeds. If the seeds germinated, she was said to be pregnant. If the wheats germinated the daughter, the barley would have a son.
Remarkably, it has been shown that this method really works, at least as a general pregnancy test. Although probably unknown at that time, hormones produced during pregnancy caused these seeds to germinate.
Wind Tunnel
Hippocrates, the father of “modern” medicine, made the wrong assumption that pregnancy can be detected by placing onions in the female vagina. If the woman's breath smelled onions the next morning, she wasn't pregnant: the idea was based on the idea that if there was no growing baby, the female uterus would be open and create a wind tunnel extending from the rectum to the mouth. If there was a baby-shaped obstacle in the womb, the woman's breath would not smell onions.
Suffice it to say that this is not medically correct.
Lifecycle
The hCG hormone was first described by medical researchers in the 1920s, and the present invention provided the opportunity to detect pregnancy by detecting hCG. The high-tech urine sticks we had today were not yet there, so what did they use instead? Unfortunately, some members of the animal kingdom would be used as a cruel tester for the job.
The urine sample from the woman was injected into an undeveloped female mouse. If there was hCG in the urine, the mouse would heat up and become sexually active and ready to mate. Initially, only mice were used, after injection the ovaries were cut and opened for examination. In a few years, the rats were replaced by rabbits. This test was called Aschheim-Zondek test, also called A-Z test.
The test was incredibly 98 percent accurate. However, the results lasted for several days and the test was unable to distinguish between a rapidly growing type of cancer called chorioepithelioma and hCG. Thus, this test was used, unintentionally, as a method of cancer diagnosis; If the patient was not pregnant, it was not cancer.
In front of everyone
A South African scientist from Cape Town, Lancelot Hogben, who developed the method further, spent his time experimenting with the hormones of humans and other creatures on clawed frogs. Amphibians have shown that they are more advantageous than mice and rabbits since their eggs can be examined much more easily.
Eventually, the South African clawed frog, whose scientific name was Xenopus laevis, turned out to be particularly convenient for human pregnancy tests. When a female frog was injected with the urine of a pregnant woman, the frog lay eggs before the end of the day. In contrast, the male frog responded to the injection by producing sperm. This much faster and more successful test spread to Europe in the 1930s and frogs became standard carriers.
Radioactive Targets
A pharmaceutical company called Warner-Chilcott in 1976; she developed a test that women could get for $ 10, which they could apply in the comfort of their own home, which resulted in 2 hours and most importantly, it didn't require frogs. The test gave 97 percent accurate results in positive results, was inexpensive and easy to use. This was a revolutionary development for the sector and provided the basis for pregnancy tests that are currently being used all over the world. The production of this test is a significant improvement from the early 1970s when radioactive labeling was used to detect hCG.
As a result, although technology has come a long way since the time of Queen Nefertiti, we still detect pregnancy by peeing on something.
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