Wednesday, November 13, 2019

Aspirin for Pain Relief and Headaches, 100 Tablets

The benefit of aspirin is far greater than its harm


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Professor Dr. E. Murat Tuzcu, side effects of aspirin, as well as the "camel ear" remains, he says.

The benefits of aspirin are always on the agenda. However, side effects are also mentioned. Professor Dr. E. Murat Tuzcu says in his article in Milliyet newspaper (26.01.09) that besides the benefits of aspirin, the side effects are like ”ears in a camel”. Tuzcu's article reads:

Ilaç Drugs with aspirin-like effects were known 3,000 years ago. Hippocrates says that a drug made from willow bark - a substance similar to aspirin today - is good for pain. Modern aspirin, first introduced in 1898, was used as a painkiller for many years. In the 1940s, a doctor in California observed that his patients, who had given aspirin for pain, did not have a heart attack. It took 25 years to understand how this positive effect was achieved.

platelets

A heart attack is caused by a clot formed inside the vein. The first building blocks in clot formation are blood cells called platelets. There are three different cells in our blood; red blood cells that carry oxygen and give blood a red color; white blood cells that protect us against germs; platelet

Because red blood cells are the heaviest cells, they are close to the center of the blood flowing; white blood cells outside; the lightest platelets circulate near the vessel wall.

If there is no condition that requires a clot in our body, platelets circulate in the blood calmly, quietly. When a place is cut, the platelets that move close to the wall immediately adhere to the torn wall and begin a change. Normally, platelets such as coins, round and flat, are smooth-surface, slippery cells. When stimulated and active, they change their shape and form recesses and protrusions on their surfaces and become sticky. This change can be compared to the recruitment of reserves in the event of mobilization. Like the protection of the borders of the country with their special clothes, equipment and weapons, and their appearance very different from their civilian status, platelets try to stop the bleeding and stop the bleeding.

Inviting platelets to enlist

Many factors stimulate and activate platelets. Some of these originate from the vessel wall, some from the blood, and some are substances secreted by platelets. We can simulate these warnings by sending letters to the reserves, by telegram, as well as making calls through radio and television channels.

The platelets, which reach the bleeding site and adhere to the wall, call on their friends to become active through the messenger substances they secrete into the blood and start to stick to each other. This creates a plug. If the incision is small, it's enough to stop the bleeding. If it is large, other substances are called for help and the clot is grown and strengthened.

How does aspirin work?

Aspirin stops the production of substances released by the platelets at the scene into the blood, activating other platelets and adhering to the wound site. Thus, a significant blow to the clot formation is reduced. However, aspirin acts only in one of several ways by which platelets become active and adhere to one another. The process, which continues in other ways, is not as effective as it used to be, but continues its work. Therefore, if someone who takes aspirin cuts his face while shaving, it will take longer than expected to stop the bleeding.

We don't necessarily have to cut off a place for platelets to start clotting. If the thin slippery layer that lays the inside of our veins, normally teflon, where nothing sticks, is scratched and damaged, they go there immediately and stick. Thus, the clot that begins, gradually grows, clogging the vein, causing a heart attack. Aspirin, to a certain extent, has a preventive effect on the occurrence of a heart attack as it stops this from the beginning.

Aspirin research

There is strong evidence that aspirin saves lives in high-risk patients. In an article published in the scientific journal of the British Medical Association (BMJ) in 1994, the data of 100 thousand patients examined in 175 studies were evaluated. It has been shown that those who have had heart attacks and strokes, patients with leg and brain vessels, and aspirin take the risk of recurrence. However, it has been shown to be useful in people with diabetes or high blood pressure, although there is no known heart disease. In this group, they were found to live healthier and longer if they were taking aspirin, albeit in the elderly.

A new study found that aspirin did not reduce the risk of heart attack but decreased the risk of stroke in women under 65 years of age. It is understood that women at high risk will benefit from aspirin even if they are not elderly.

Side effects of aspirin

Here's to the side effects of aspirin. They were also taken into account in this research. The most important side effect of aspirin is that it can cause bleeding. The most terrible bleeding, brain haemorrhage. Fortunately, this is only seen in one of the 10,000 aspirin sites. Stomach bleeding is more frequent. Aspirin is not seen between 1 and 2 per thousand; If you take aspirin, this risk increases to around 3 per thousand. Let's make an account; If we give aspirin to 1000 people who have had a heart attack, we prevent 40 new heart attacks that will occur in a month, and if we continue, we will protect 40 patients from new heart attacks in the next 2 years. Of these 1000 people, 3 or 4 suffer from bleeding in the stomach within a year. To take or not to get useful? Isn't the answer clear?

Should people who do not have cardiovascular disease should also take it? It is more difficult to answer the question m Should I take aspirin? In for those who have no cardiovascular disease and who have a high risk of being ill. To be able to respond correctly, the patient's risk of heart attack or stroke should be compared with the risk of bleeding.

4 studies in the United States and the United Kingdom, a known cardiovascular disease, some 50 thousand people, some aspirin-like aspirin, but similar to other hollow pill (placebo) was given. Aspirin patients had less heart attacks. It is better to dwell on this point. Aspirin, given to reduce a person's risk of having a heart attack from 3 percent to 2 percent within a year, is still very useful, although half the risk of bleeding increases. On the other hand, the risk of heart attack is half the risk of bleeding, even if we reduce it to 0.3 percent. It's best not to give aspirin to such a patient.

What should be the dose of aspirin?

We know that 75 mg aspirin is enough to prevent platelets from sticking together. The result of studies conducted on 10 thousands people is that there is no need for high doses. Nevertheless, I strongly advise you to decide with your doctor whether to take aspirin or not.


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Answer 5 questions about aspirin


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The risk of serious or even fatal bleeding in the stomach of those taking aspirin on a daily basis after exacerbation or stroke is higher. This risk is higher than previously thought, writes Lancet, based on research findings.

According to scientists, in order to reduce the risks, older people should take in addition to aspirin as well as PPI (proton pump inhibitor) tablets that protect the culture.

At the same time, doctors insist that aspirin intake plays an important role in preventing seizures and outweighs other risks.

For this reason, they do not recommend taking aspirin immediately.

Patients should consult a doctor before any changes to the medication regimen, the authors note.

"Life Pills"
As a rule, after a stroke or a stroke, doctors advise the person to take aspirin until the end of his life.

It is also known that aspirin can cause gastric bleeding.

So far, research on this issue has been conducted only for people over 75 years of age.

And the results of these studies have revealed that in this age group, the risk of serious gastric bleeding is low.

Posted by GETTY IMAGES
In Britain, more than half of those taking aspirin in the age of 75 are over. Scientists from the University of Oxford compared the risks of taking aspirin to those of this age group.

They observed 3,166 patients receiving aspirin.

It was found that the percentage of cases of gastric bleeding and other fatal complications among those under 65 was less than 0.5% (on average, one in every 200 drug users).

However, in the age group of 75-84, this coefficient increased, reaching an average of 3 persons or about 1.5% for every 200 people.

It has been found that as the patient's age increases, the risk of aspirin gastric bleeding is also on the rise.

According to existing rules in the UK, doctors write PPI pills in addition to aspirin therapy for patients at high risk of gastric bleeding.

However, there is a need to specify who is at high risk.

According to a leading researcher, Professor Peter Rothwell, most drugs over the age of 75 are not prescribed.

Posted bySCIENCE PICTURE CO / SCIENCE PHOTO LIBRARY
I take aspirin every day - should I take action?
Professor Helen Stokes-Lampard of the Royal College Hospital says "patients who take aspirin should not panic."

"For a long time, aspirin users are advised to discuss this with their doctor or pharmacist."

Why is it not advisable to cut off aspirin intake?
It has been shown that sudden withdrawal of aspirin increases the risk of heartburn or stroke.

You need to talk to your doctor before taking this step. If the doctor advises, you can gradually reduce the number of pills taken.

What should be done to protect the stomach of those over 75 years of age and those who take aspirin on a daily basis after heart attack and heartburn?
Patients in this age group have a lower risk of gastric bleeding. Professor Rothwell does not recommend that people of this age group take supplements.

However, scientists recommend these patients to appear to the doctor every 3-5 years.

What should those who take aspirin daily but do not suffer from heart disease?
Researchers advise carefully considering the decision to take aspirin for a healthy person. They consider it necessary to consult a doctor before making that decision.

What are the health risks of PPI drugs that are culturally protected?
All medicines have certain benefits and risks. The decision on whether or not to take this drug should be made individually, based on the advice of a physician. In certain cases, patients may experience excessive abdominal pain, meteorism, and gastric infections after the drug is administered.


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New research on aspirin: 'safe' for patients with stroke due to cerebral hemorrhage


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A recent study of patients with stroke due to cerebral hemorrhage revealed that patients may use aspirin to reduce the risk of heart trouble and new stroke.

Aspirin dilutes the blood, so doctors are cautious about using this medicine to prevent further bleeding.

However, a new study published in the world-famous medical journal Lancet showed that aspirin does not increase or even reduce the risk of new bleeding in the brain.

Experts stress that more research is needed despite "strong data" on this issue.

Aspirin should be taken only on the advice of a doctor and should not be given to children under 16 years.

Research has yielded results! 19 thousand people say that the use of aspirin attention ...
Benefits and risks of aspirin
Aspirin is often used as painkillers and antipyretics.

Aspirin can be taken at a daily dose of 75 mg to reduce blood risk of heart attack and stroke.

Most strokes are caused by the formation of a clot in the brain vessels. However, there are also strokes caused by bleeding.

Aspirin can dilute blood and cause more bleeding in patients.

Also, aspirin is not a safe drug for everyone.

It can cause indigestion and, more rarely, stomach ulcers.

Children under the age of 16 can only be given with the advice of a doctor.

Guideline updated: Aspirin is no longer recommended as a preventative for those without disease
Aspirin in children, a rare but serious disease and cause damage to the brain and liver Reye syndrome is said to cause.

The research, published in Lancet magazine, is presented to the European Stroke Organization Conference, which began in Milan.

A new aspirin study: Decreases heart attack risk by 11 percent, increases risk of dangerous bleeding by 43 percent

What do the experts say?
This research does not prove that aspirin prevents the risk of stroke, but suggests that it reduces the risk. It also doesn't mean that aspirin can always be taken safely.

However, it may be beneficial for patients who have suffered a stroke as a result of cerebral hemorrhage to use low-dose aspirin daily.

In a study conducted on 537 UK patients, the risk of new bleeding was reduced. However, it is not yet clear that all patients in this position will have such an impact in real life.

Professor Rustam Salman, head of the research team at the University of Edinburgh, says:

"The right thing to do now is not known. Doctors are hesitant to give aspirin and similar medications to patients with stroke like this. There is no guideline that can be used in the UK and Europe to provide enough data. . "

Professor Metin Avkıran of the British Heart Foundation, which finances the research, said: "About one-third of stroke sufferers suffer from brain strokes while taking blood-thinning medications such as aspirin to reduce the risk of heart attack and clot stroke. There is strong evidence that they can continue to take these medications with liberating potential. "

However, patients with any concerns are advised to consult a doctor before making any changes to their medication.

Doctors recommend the following to reduce the risk of stroke:

Healthy eating
Regular exercise
No smoking
Avoiding excess alcohol


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The benefits of aspirin you know from skin health to flower care


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Aspirin, found in almost every home, has an antipyretic pain relief properties, as well as numerous unknown skills.

Do not say aspirin; The inexperience of this drug is great both cheap and easy to find. Here are the unknown benefits of aspirin!

1. Used to treat acne
Used to treat acne
After crushing 2 aspirin and mixing with lemon juice, apply on your acne. You can make this mixture especially before going to the sun.

2. Painless solution to insect bites
Painless solution to insect bites
After insect or fly bites, you can apply crushed and slightly aspirated aspirin to the sore or sore area.

3. Eliminates skin blemishes
Eliminates skin blemishes

3 tablespoons yogurt, 1 tablespoon honey and a few aspirin crush and mix. You can mask the mixture on your face and wait 15 minutes, then rinse.

4. Effective solution to dandruff
Effective solution for dandruff
Solve the problem of dandruff dandruff, especially in men's hair, now very tin. Mix 2 pieces of crushed aspirin into your shampoo and get rid of all dandruff.

5. Aspirin drug for sensitive skin
Aspirin for sensitive skin
Especially if you have oily or sensitive skin, you can crush a few aspirin and mix with water, then mask your skin. The aspirin mask is the most natural way to dry the oil on your sensitive skin.

6. Effective in foot care
Effective in foot care
Mash 7 aspirin and add half a tablespoon of lemon juice to form a mixture. Apply this mixture directly to your feet and soles. Then cover your feet with a warm cover and wait. After waiting for 10 minutes, you will notice that your feet are soft.

7. The secret of healthy and shiny hair
The secret of healthy and shiny hair
For healthy and shiny hair, aspirin in a warm glass of water and wait. Then wash your hair with water and do not rinse for 15 minutes. You will see the difference.

8. Eliminates sweat stains on clothes
Eliminates sweat stains on clothes
Soak the clothes you can not get rid of the stains the night before, soak in aspirin warm water soaked. Then rinse normally.

9. The way to get rid of soap stains in the bath aspirin
Aspirin to get rid of soap stains in the bathroom
Crush 5 aspirin and mix into water and apply to the area you want to clean. After waiting for a while, wipe with a cloth and rinse with water.

10. Extends the life of flowers
Extends the life of flowers
You can extend the life of your flowers by throwing 1 or 2 crushed aspirin into the flower water in the vase.

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history

Salicin, the major painkiller chemical in aspirin, has been used as a pain reliever since the 5th century BC. Some people in Hippocrates, among them, have discovered that the wills of bark and leaves of the willow tree, or medications prepared by using them, relieve pain. In the 1800s, researchers found that the emitter was a painkiller chemical. The negative effects of Salicin on stomach were so great that it was 1915 to reduce and put it on the market. The first manufacturer was the German Bayer.

Aspirin?

The first letter of the word aspirin comes from the first letter of the chemical used to reduce stomach effects of salicin: Acetyl chloride. The next 4 letters come from the plant where salicin is produced: Spirea ulmaria. The last 2 letters come from the jewelry that was put at the end of the drug names: -in.



While aspirin has been used as a painkiller for headaches and other pains for more than 100 years, it was called “miracle medicine başında in the early 70s because of its pain relieving effect and its benefits to heart patients. As a result of more than thirty years of research, aspirin has been found to prevent first and subsequent heart attacks, stroke, and other cardiovascular events in people with cardiovascular disorders such as coronary artery disease or high blood pressure. BASE. According to the Food and Drug Administration (FDA), 20 billion tablets are consumed each year in the United States.



Proven Facts About Aspirin

Aspirin treatment reduces the risk of heart attack and other possible heart attacks.

Especially in emergency situations such as heart attacks, chewing rather than swallowing makes the drug enter the bloodstream more quickly.

Aspirin is a prophylactic agent for stroke and transient ischemic attack (TIA) caused by blockage in the cerebral vessels.

In recent years, it has been discovered that it has a protective effect on some cancers, especially colon cancer.

Aspirin reduces the risk of a first heart attack by 32% and reduces the risk of heart attack, stroke and vascular death by 15%. a study on 22,000 doctors in the USA has shown that aspirin users have 50% fewer heart attacks.

Dose

Most studies show that aspirin at low doses (81 milligrams) per day is effective in preventing heart attacks and stroke. In general, taking more than 325 mg per day has no added benefit in terms of cardiovascular health. On the contrary, as the dose increases, the side effects of the digestive system increase.

Available in tablet form on the market. In addition, for long-term use to reduce the side effects of the stomach, not in the stomach, but also in the intestine soluble form (enteric coated) has been made.



Aspirin advertising tool, 1929

Usage areas

Painkiller

Chemically, aspirin is known as ASA (acetylsalicylic acid). It stops pain and burning by blocking the enzyme called cyclooxygenase (COX). When this enzyme is blocked, the body cannot produce more than prostagland, a chemical that provides wound signaling and pain sensation. For example, when a person strikes his head, the damaged tissue in the head releases chemicals to make the person feel pain. Some of these chemicals are prostaglandins. Therefore, blocking their production will reduce the pain felt from the wound. However, aspirin is not a cure for the causative agent (the wound itself), but it helps to reduce the pain signals that reach the brain from nerve cells.

Prevention of Blood Coagulation

Blocking prostaglandin production not only reduces pain but also prevents clot formation. Some prostaglandins cause platelets (platelets = blood clotting elements) to combine to form a clot. If prostaglandin production is slowed or inhibited, clot formation is also slowed or inhibited. Therefore, aspirin belongs to a group of drugs called antiplatelet. Antiplatelet drugs, including aspirin, are drugs that reduce the ability of platelets to bind to each other and prevent clot formation. Aspirin prevents the formation of clots and prevents the formation of clusters in the arteries that can trigger heart attacks. This effect persists for 5 days after discontinuation of aspirin.

Cardiovascular Diseases

By helping to prevent blood clot formation, aspirin provides sufficient blood flow through the arteries, thereby reducing the risk of heart attacks in men and women. In addition, if the aspirin is taken during or immediately after the crisis, it reduces the damage of the crisis. Aspirin is also used after vascular interventions such as angioplasty and coronary bypass surgery.

People who can benefit from the use of aspirin

In general, aspirin is recommended for patients in the following categories:

Patients with known coronary artery disease,

Patients with heart attacks or angina,

Patients with serious risk factors for heart disease (smokers, inadequate exercise, high cholesterol or triglyceride levels, diabetes or high blood pressure),

Those who had bypass surgery,

Risk of heart attack,

People with mini-stroke (TIA) or ischemic stroke.

Patients who cannot use aspirin may be given a different drug called clopidogrel (Plavix, Pingel, Karum, etc.). Clopidogrel is also given to people with stents. According to the study, aspirin and Clopidogrel co-administration to people who can take aspirin has a great effect on preventing clot formation. The combination of aspirin-clopidogrel has been shown to benefit people at risk for sudden (acute) coronary events.

Aspirin should or should not be used with caution in the following cases

People with allergies to aspirin,

In people with uncontrolled hypertension,

It can cause stomach irritations and excessive bleeding when taken with aspirin.

Chronic bowel problems including ulcers, gastritis, inflammatory bowel disease and bleeding,

NSAI (Non Steroid Antiinflamatur drugs = non-steroid rheumatic pain medication)

Aspirin may increase excessive bleeding in people who are undergoing surgery (many surgeons stop using aspirin 10 days before surgery), but for dental interventions (including tooth extraction), there is no need to stop aspirin,

In pregnant women (especially during the first and third trimesters *), since aspirin may lead to delayed delivery and complicate delivery (trimestir = name given to 3-month periods in pregnancy),

The use of aspirin in children under 18 years of age with chickenpox or flu can cause Reye's syndrome, a fatal disease.

Use

Tablets dissolved in the intestine should be swallowed without chewing. However, it can be chewed for immediate effect in emergencies such as heart attack. Intestinal insoluble forms can be taken with food or antacids (antacid = alkaline drugs used to reduce stomach acid content; dank, talcid, rennie, etc.) to reduce the side effects of the stomach, or with stomach acid-reducing (stomach protection) drugs (nexium, panto, etc.).

Side effects seen in some patients taking aspirin

Digestive system disorders: ulcers in the stomach, pain, burning, nausea, vomiting, internal bleeding, stomach or intestinal perforations,

Swelling around the face (as a result of allergies),

Asthma attack (as a result of allergy),

Tinnitus when used in high doses,

Brain hemorrhage that may cause a stroke.

Patients should consult their physician for the use of aspirin. Since aspirin is an over-the-counter medicine, many people think they can take aspirin safely every day. However, due to the excessive use of aspirin and other over-the-counter pain medications, thousands of people are hospitalized every year, especially with serious stomach problems.

As a result, aspirin is one of the miracle drugs of our time. However, its use should be under the control of a doctor and the doctor should be consulted about its benefits and risks.


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According to a large-scale study of scientists; Aspirin should never be used to prevent heart disease without doctor's advice as it increases the risk of dangerous bleeding. Experts agree that uncontrolled aspirin can be used to prevent illness rather than harm to a person.


Yeditepe University Kosuyolu Hospital Chief Physician and Internal Medicine Specialist Assoc. Dr. Hakan Terekeci in England between the ages of 50 to 74 people by reviewing the records said that an assessment was made, as a result of this assessment of people who use daily aspirin increased risk of gastrointestinal bleeding more than 40 percent was observed. Accordingly, the benefits and harms of aspirin use has been discussed in public. A study was conducted at King's College Medical School before this study. In the study, which was completely based on healthy individuals, it was stated that the protection with aspirin from stroke and cardiovascular diseases would not be worth it compared with the risk of bleeding. In the light of these, aspirin is not recommended for the prevention of primary cardiovascular and stroke risk individuals in England. However, aspirin protection of people who have had a heart attack, stent implantation and paralysis is secondary protection. Aspirin should be used for secondary prevention. '' said.


'We Do Not Recommend Uncontrolled Aspirin Use'

Yeditepe University Koşuyolu Hospital Chief Physician and Internal Medicine Specialist Assoc. Dr. Hakan Terekeci, aspirin was recommended to prevent cardiovascular diseases over a period of more than 30 years. For about 15 years, aspirin was used especially in patients at risk of stroke and stroke. Opinions about the use of aspirin have been reported in various guidelines, but studies have shown that the risk of bleeding increases over time. Aspirin has been on the agenda again because of the screening of 164 thousand patients and the health problems related to bleeding in the UK. Also, even if not included in the guidelines, many people use aspirin without going to the doctor. It is extremely important to raise public awareness that this is a very wrong practice. "


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Is aspirin good for hair? Hair mask made with aspirin


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Did you know that aspirin, which is generally known for its pain relief and antipyretic properties, is sold only in pharmacies to prevent hair loss? Aspirin hair mask, which is frequently used by hair care professionals; It helps to open the pores on the scalp and helps the hair look more beautiful and vibrant. Here are the benefits to aspirin hair and hair mask recipe made with aspirin:


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Aspirin, one of the most effective pain relievers, which we generally prefer to use when our headaches, is found to prevent hair loss and dandruff thanks to the high rate of D2 prostaglandin.


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The hair mask with aspirin, which contains plenty of salicylic acid in its components, significantly eliminates the formation of dandruff caused by frequent shampoo use.

In order to prepare the hair mask with aspirin that eliminates dandruff formation in the hair, first make one powder by beating it in the mortar. Then add aspirin powder into your shampoo. When you shampoo your hair shampoo for 5 minutes in your hair and rinse your hair with plenty of water.


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- Aspirin mask that gives hair shine and vitality thanks to its salicylic acid in its components; On the other hand, it leads the hair bottoms to breathe more easily.

- Aspirin hair mask, a perfect exfoliation; deeply cleansing the hair, preventing fungal formation on the hair.

The mask with aspirin, which is also good for hair dryness; cleans the hair from dead cells.




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HOW TO MAKE A HAIR MASK WITH ASPIRINE?

Powder 2 aspirin. Add to your natural shampoo and mix.

You can use the massage during the shower. This method removes the dandruff on the hair.


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Another method that can be done with aspirin is to put 6 aspirin into 1 cup of warm water to melt. Rub this mixture by rubbing your hair.

This method will ensure that your hair color remains constant, especially dyed hair will remain the same color for a long time.

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Get a big glass of water. Put 30 aspirin and 1 tablespoon of carbonate in water. After stirring well, warm the mixture in the coffee pot until dark.

After the shower, apply the whole mixture to moisturize your hair and leave for 30 minutes. Rinse with warm water.


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Aspirin Hair Mask Recipe (Suna Dumankaya)

Materials:

1 teaspoon sweet almond oil
4 powdered aspirin
1 teaspoon of powdered brewer's yeast
Thyme oil in a coffee cup

Preparation of:

After thoroughly mixing all ingredients in a bowl, apply the mixture to your hairs, just like dyeing.

Wait 2 hours and rinse your hair with plenty of water.

If you apply this mask to your hair once a week, you can stop hair loss and ensure that new hair strands grow stronger and thicker.


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HOW IS HAIR CARE MADE WITH ASPIRINE?

Materials:

1 cup water
1 tablespoon carbonate
30 aspirin

Preparation of:

After pouring one cup of water into a pot and boiling, add 30 aspirin to the boiling water and wait for the aspirins to dissolve.

When the aspirins melt, add 1 tablespoon of carbonate to the pot.

Mix all ingredients thoroughly and let the hair mask warm with aspirin.

When you leave the aspirin mask to warm, wash your hair and rinse with a hair towel.

With a towel, rinse your hair and hair bottoms with aspirin hair mask massage massage.

Wait 30 minutes and wash your hair with plenty of water and shampoo.

With this mask you can get rid of dandruff in your hair in a short time.

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