Aspirin - Everything You Need to Know About Your Heart
history
Salicin, the major painkiller chemical in aspirin, has been used as a pain reliever since the 5th century BC. Some people in Hippocrates, among them, have discovered that the wills of bark and leaves of the willow tree, or medications prepared by using them, relieve pain. In the 1800s, researchers found that the emitter was a painkiller chemical. The negative effects of Salicin on stomach were so great that it was 1915 to reduce and put it on the market. The first manufacturer was the German Bayer.
Aspirin?
The first letter of the word aspirin comes from the first letter of the chemical used to reduce stomach effects of salicin: Acetyl chloride. The next 4 letters come from the plant where salicin is produced: Spirea ulmaria. The last 2 letters come from the jewelry that was put at the end of the drug names: -in.
While aspirin has been used as a painkiller for headaches and other pains for more than 100 years, it was called “miracle medicine başında in the early 70s because of its pain relieving effect and its benefits to heart patients. As a result of more than thirty years of research, aspirin has been found to prevent first and subsequent heart attacks, stroke, and other cardiovascular events in people with cardiovascular disorders such as coronary artery disease or high blood pressure. BASE. According to the Food and Drug Administration (FDA), 20 billion tablets are consumed each year in the United States.
Proven Facts About Aspirin
Aspirin treatment reduces the risk of heart attack and other possible heart attacks.
Especially in emergency situations such as heart attacks, chewing rather than swallowing makes the drug enter the bloodstream more quickly.
Aspirin is a prophylactic agent for stroke and transient ischemic attack (TIA) caused by blockage in the cerebral vessels.
In recent years, it has been discovered that it has a protective effect on some cancers, especially colon cancer.
Aspirin reduces the risk of a first heart attack by 32% and reduces the risk of heart attack, stroke and vascular death by 15%. a study on 22,000 doctors in the USA has shown that aspirin users have 50% fewer heart attacks.
Dose
Most studies show that aspirin at low doses (81 milligrams) per day is effective in preventing heart attacks and stroke. In general, taking more than 325 mg per day has no added benefit in terms of cardiovascular health. On the contrary, as the dose increases, the side effects of the digestive system increase.
Available in tablet form on the market. In addition, for long-term use to reduce the side effects of the stomach, not in the stomach, but also in the intestine soluble form (enteric coated) has been made.
Aspirin advertising tool, 1929
Usage areas
Painkiller
Chemically, aspirin is known as ASA (acetylsalicylic acid). It stops pain and burning by blocking the enzyme called cyclooxygenase (COX). When this enzyme is blocked, the body cannot produce more than prostagland, a chemical that provides wound signaling and pain sensation. For example, when a person strikes his head, the damaged tissue in the head releases chemicals to make the person feel pain. Some of these chemicals are prostaglandins. Therefore, blocking their production will reduce the pain felt from the wound. However, aspirin is not a cure for the causative agent (the wound itself), but it helps to reduce the pain signals that reach the brain from nerve cells.
Prevention of Blood Coagulation
Blocking prostaglandin production not only reduces pain but also prevents clot formation. Some prostaglandins cause platelets (platelets = blood clotting elements) to combine to form a clot. If prostaglandin production is slowed or inhibited, clot formation is also slowed or inhibited. Therefore, aspirin belongs to a group of drugs called antiplatelet. Antiplatelet drugs, including aspirin, are drugs that reduce the ability of platelets to bind to each other and prevent clot formation. Aspirin prevents the formation of clots and prevents the formation of clusters in the arteries that can trigger heart attacks. This effect persists for 5 days after discontinuation of aspirin.
Cardiovascular Diseases
By helping to prevent blood clot formation, aspirin provides sufficient blood flow through the arteries, thereby reducing the risk of heart attacks in men and women. In addition, if the aspirin is taken during or immediately after the crisis, it reduces the damage of the crisis. Aspirin is also used after vascular interventions such as angioplasty and coronary bypass surgery.
People who can benefit from the use of aspirin
In general, aspirin is recommended for patients in the following categories:
Patients with known coronary artery disease,
Patients with heart attacks or angina,
Patients with serious risk factors for heart disease (smokers, inadequate exercise, high cholesterol or triglyceride levels, diabetes or high blood pressure),
Those who had bypass surgery,
Risk of heart attack,
People with mini-stroke (TIA) or ischemic stroke.
Patients who cannot use aspirin may be given a different drug called clopidogrel (Plavix, Pingel, Karum, etc.). Clopidogrel is also given to people with stents. According to the study, aspirin and Clopidogrel co-administration to people who can take aspirin has a great effect on preventing clot formation. The combination of aspirin-clopidogrel has been shown to benefit people at risk for sudden (acute) coronary events.
Aspirin should or should not be used with caution in the following cases
People with allergies to aspirin,
In people with uncontrolled hypertension,
It can cause stomach irritations and excessive bleeding when taken with aspirin.
Chronic bowel problems including ulcers, gastritis, inflammatory bowel disease and bleeding,
NSAI (Non Steroid Antiinflamatur drugs = non-steroid rheumatic pain medication)
Aspirin may increase excessive bleeding in people who are undergoing surgery (many surgeons stop using aspirin 10 days before surgery), but for dental interventions (including tooth extraction), there is no need to stop aspirin,
In pregnant women (especially during the first and third trimesters *), since aspirin may lead to delayed delivery and complicate delivery (trimestir = name given to 3-month periods in pregnancy),
The use of aspirin in children under 18 years of age with chickenpox or flu can cause Reye's syndrome, a fatal disease.
Use
Tablets dissolved in the intestine should be swallowed without chewing. However, it can be chewed for immediate effect in emergencies such as heart attack. Intestinal insoluble forms can be taken with food or antacids (antacid = alkaline drugs used to reduce stomach acid content; dank, talcid, rennie, etc.) to reduce the side effects of the stomach, or with stomach acid-reducing (stomach protection) drugs (nexium, panto, etc.).
Side effects seen in some patients taking aspirin
Digestive system disorders: ulcers in the stomach, pain, burning, nausea, vomiting, internal bleeding, stomach or intestinal perforations,
Swelling around the face (as a result of allergies),
Asthma attack (as a result of allergy),
Tinnitus when used in high doses,
Brain hemorrhage that may cause a stroke.
Patients should consult their physician for the use of aspirin. Since aspirin is an over-the-counter medicine, many people think they can take aspirin safely every day. However, due to the excessive use of aspirin and other over-the-counter pain medications, thousands of people are hospitalized every year, especially with serious stomach problems.
As a result, aspirin is one of the miracle drugs of our time. However, its use should be under the control of a doctor and the doctor should be consulted about its benefits and risks.
30AXX
Genuine Bayer Aspirin 325mg Coated Tablets | #1 Doctor Recommended Aspirin Brand | Pain Reliever | 200 Count
